stryker@phy.ucsf.edu 415 476-8371 Ph Medical Science Building S-762 University of California San Francisco, CA 94143-0444

Michael P Stryker

• PhD in Neurophysiology awarded by The Massachusetts Institute of
  Technology, Cambridge, Massachusetts
• Professor, Department of Physiology
• Faculty, Herbert W. Boyer Program in Biological Sciences (PIBS)
• Faculty, UCSF Neuroscience Graduate Group
• Faculty, UCSF/UCB Joint Graduate Group in Bioengineering
• Faculty and Executive Committee, UCSF Program in Bioengineering
  

Stryker Lab
Keck Center for Integrative Neuroscience

Development and Plasticity of the Central Visual System
We wish to understand how the brain wires itself up correctly. Our laboratory's major focus has been the role of neural activity in the development of precise connections in the brain, and in the capacity of the brain to change its connections and responses in later life. Nearly all of the work of the laboratory is on the developing visual cortex. Connections here are highly precise in adults, and the precision appears to result from activity-dependent plasticity operating to refine connections that are initially more diffuse. We have developed new methods of imaging brain activity that allow us to investigate these issues in genetically altered mice and in larger animals. In addition to imaging, we use electrical recording of single neurons together with a number of anatomical and biophysical techniques. We also collaborate with colleagues on mathematical and computational models of cortical function in relation to visual perception.

PUBMED Link to Publications

Link to Lab Abstracts

© Program in Bioengineering, University of California
1700 4th St. MC0775, San Francisco, CA 94158-2330
Ph: 415 514-9242 // Fax 415 476-6022

Please direct all web comments to Jeffery Lowers

web site by aeronet